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Dropping Chase Edmonds after the first few weeks was understandable, though he now needs to be rostered in all formats given David Johnson’s back injury. Even if Johnson plays, there’s reason to believe he would split more work with Edmonds than usual, paving the way for the latter to improve on his season-high 11 touches from last week. 

Against the Cowboys in Week 5, Jake Kumerow played 48 snaps and ran 20 routes. He only drew two targets, but one was a deep target and he was tackled at the one-yard line on the other. The pride of UW-Whitewater makes for a fine desperation dart throw against the Lions on Monday Night Football. One with potential longer-term viability given Davante Adams’ injury .

Logging a top 24 finish in three of five games this season, Courtland Sutton now sits inside the top 10 WRs in fantasy. However, he has yet to log a top-five WR finish this season. Heading into Week 6, his matchup with Malcolm Butler has the perfect conditions to yield that monster finish that gamers want.

Terry McLaurin’s 114.6 (95th-percentile among qualified wide receivers) Speed Score has helped pave the way to his 308 (No. 31) receiving yards on only 19 (No. 39) receptions. Xavien Howard’s 18.9 (No. 74) Fantasy Points Allowed Per Game, coupled with his struggles in separation, make McLaurin another top WR play in Week 6.

Starting any Washington player not named Terry McLaurin is truly going to the bottom of the barrel. That said, when what we find at the bottom of the barrel is a future Hall of Fame running back facing a league-worst rushing defense, one can’t help but have their curiosity piqued. Considering that this may be the closest we see Adrian Peterson get to 100-plus yards all season, throw him into DFS lineups and enjoy the ride.

Name any advanced stat or metric for running backs on PlayerProfiler.com this season and you can probably find Derrick Henry’s name somewhere within the top 10. The Titans have thrived in the running game this season, averaging 27.8 (No. 11) team run plays per game while granting Henry 15 (No. 9) red zone touches. Those chasing high volume players at discounted prices would be doing it wrong by avoiding Henry this week.

Alvin Kamara is top-five among running backs in Weighted Opportunities, receptions and receiving yards. He leads in evaded tackles and is second in Juke Rate. With Christian McCaffrey not on the main slate, Kamara becomes the best running back play of the week. Take advantage of him being priced below Ezekiel Elliott and Dalvin Cook on both FanDuel and DraftKings.

Austin Hooper will have the opportunity to feast on a bad Arizona defense in Week 6. The Cardinals have allowed the most yards, touchdowns and fantasy points to tight ends. Hooper received a $500 bump in price on DraftKings, but is still $2,000 cheaper than Travis Kelce. Lock him in as the best tight end play two weeks in a row.

With a high draft pedigree and plus results in College Dominator Rating and Speed Score, there’s no reason to throw J.J. Arcega-Whiteside in the trash. If your leaguemates are souring on a late first round dynasty pick, or yearning for an instant producer instead of a player not quite ready to contribute, he is a premier buy low.

The Chris Herndon suspension buying window has transformed into a post-suspension buying window fueled by a hamstring pull. Herndon is expected to be out until Week 8, which still leaves a half-season of production on the table for an offense that is about to get their starting QB back and where playmakers are in short supply.

With Sam Darnold set to return from his bout with mono, Robby Anderson’s fantasy football outlook subsequently returns from the grave. A true boom- or-bust field stretching archetype, Anderson boasts 4.41 (92nd-percentile among wide receivers) speed with the ability to beat defenses over the top. His impending breakout game looms large, though it might have to wait one more week.

The Broncos have allowed five rush TDs across the first five weeks and also let Leonard Fournette rush for 225 yards. Their defensive line ranks No. 27 in run blocking per Football Outsiders. Derrick Henry beats stacked fronts against bad teams. That’s it. Fire him up in cash games and see about making a play for him in redraft ahead of his next blowup game.

While other DFS gamers will struggle to navigate the 49ers backfield, sharps will be finding a way to fit Matt Breida into their lineups. He has been showcasing why athleticism matters in athletics, parlaying his 127.7 (89th-percentile among qualified running backs) SPARQ-x score into a 7.7-percent (No. 6) Breakaway Run Rate.

With Sammy Watkins leaving Week 5 early, the undrafted Byron Pringle from Kansas State finally got a shot and he did not disappoint, hauling in six of nine targets for 103 yards and a score. Pringle has only run 35 routes on the season, but has a 21.6-percent (No. 3) Hog Rate. With more snaps and the trust of Mahomes, Pringle will continue to pop in this offense.

Since Drew Brees’ injury, Alvin Kamara averages a 79-percent Snap Share and 16.3 rush attempts per game in the Saints’ offense. He notably retained his receiving role under Teddy Bridgewater with 6.7 targets per contest. As elusive as they come, Kamara ranks No. 1 with 47 in Evaded Tackles, showing the ability to create on his own in this offense. 

After a rough start for all Cleveland players, Odell Beckham saw his salary reduced to $6,800 prior to Week 6. Positively for the entire Brown’s offense, Seattle ranks bottom-ten in sacks and QB Hits, affording Baker Mayfield extra time in the pocket. This raises Beckham’s potential ceiling and creates an opportunity to land a GPP-winning score.

Because the Rams run 46 pass plays per game, staying on the field as often as possible gives Robert Woods an incredibly high target floor and ceiling each week. Additionally, Brandin Cooks is questionable to play this week due to a concussion he suffered in Week 5. If he doesn’t suit up, the volume ceiling is limitless for Woods and Cooper Kupp.

Based on his efficiency in prior years, current volume and current red-zone work, Alvin Kamara is likely to start scoring touchdown soon. He faces Jacksonville on Sunday. A week ago Christian McCaffrey went to town on them for over 40 fantasy points. Dropping 30 on them is well within Kamara’s range of outcomes.

Although Jacoby Brissett has 10 passing touchdowns, No. 8 among qualified quarterbacks, he is middle-of-the-pack in most passing metrics on Player Profiler. Touchdown regression was likely, and his eight-to-three Interceptable Throws to Money Throws ratio exemplifies that.

On the season, Mike Evans is tied for the lead among wide receivers with 12 Deep Targets, leads the position with 619 yards of  Total Target Distance and is averaging 20.4 (No. 5) yards per reception. Because of his role and shadow-ability, Evans is the ultimate high-ceiling/low-floor wide receiver.