PlayerProfiler is home to award-winning dynasty rankings and tools. Our Dynasty Deluxe package includes complete Dynasty Rankings, Rookie Rankings, Trade Analyzer, Draft Planner, Mock Drafts, and more. Check it out! Below, Wolf Trelles-Heard gives you five fantasy football stacks to attack.
I’ve been utilizing fantasy football stacks for as long as I can recall. There’s nothing like watching your point total spike when your quarterback and pass-catcher connect for a big play. I still remember the rush of having Peyton Manning and Reggie Wayne or Kurt Warner and Larry Fitzgerald in my lineups back in the day. Ever since, I’ve made it a point to leave every draft with at least one strong QB-WR or QB-TE pairing.
Stacking maximizes your roster’s ceiling, and when it hits, it gives your team a serious edge in win rate. Everyone already knows Joe Burrow and Ja’Marr Chase are the gold standard, so I’m skipping them and focusing on the next wave of fantasy football stacks that I think can deliver league-winning upside in 2025.
1. QB Dak Prescott & WR CeeDee Lamb

Dak Prescott’s Advanced Metrics
Unless you’re drafting at 1.01 or 1.02, you won’t get Chase. Your next best WR to target for one of the major fantasy football stacks is CeeDee Lamb, who’s going anywhere from 1.03 to 1.08 depending on the format. To me, Lamb is in Chase’s tier:
- Proven ceiling. Lamb was the WR1 overall in 2023, going nuclear in the second half that year. He amassed 135 catches, 1,749 yards, and 12 scores, good for 23.7 fantasy PPG – same as Chase in his triple crown 2024 season. Meanwhile, Dak Prescott has produced five top 10 finishes and three seasons throwing for over 4,400 yards in his career.
- Pass-heavy attack. The Cowboys should be in plenty of shootouts thanks to a shaky defense and a RB room consisting of Javonte Williams, Miles Sanders, and Jaydon Blue. This offense runs through Prescott and Lamb, not the ground game.
- Locked-in security. Dallas isn’t shelling out $376 million to this QB-WR combo over the next four seasons just to hand off to mediocre backs. If they’re going to win the NFC East and make noise in the playoffs, it’ll be on the backs of Prescott and Lamb.
I love grabbing Lamb in the mid-first and waiting to scoop up Prescott later. The QB for America’s Team has the same high-yardage upside as Burrow – without the early draft price. This stack carried teams to titles in 2023 and has the potential to do it again in 2025.
2. QB Jalen Hurts & WR A.J. Brown
The Eagles’ top dog in the passing game comes at a slightly cheaper price than Chase or Lamb, and while he doesn’t have the same WR1 overall ceiling, A.J. Brown is a top 5 threat.
Philadelphia will always lean on the run with Jalen Hurts at the helm, but its passing game has an extremely concentrated target tree that features Brown front and center.

A.J. Brown’s Advanced Metrics
Last season, in what many considered a “down” year for the superstar wideout, he ranked:
- No. 1 in PlayerProfiler’s Explosive Play Rating
- No. 1 in route participation percentage
- No. 2 in air yards share
- No. 2 in yards per route run
- No. 3 in fantasy points per route run
- No. 4 in yards per target
- No. 4 in Dominator Rating
Brown is a great round 2 target, and managers who stack him with the reigning Super Bowl MVP a round or two later create a lethal combo. Since becoming a starter, Hurts has never averaged fewer than 21.3 fantasy PPG and has four consecutive top 10 overall finishes.
His passing numbers will never match the elite volume throwers, but Hurts makes up for that in abundance with his legs. He averages 695 rushing yards a season and has an absurd 52 rushing TDs since 2022.
Having this duo could be a death blow to your league mates, the kind that can swing fantasy matchups by itself.
3. QB Baker Mayfield & WR Mike Evans
One of these days, the man with 11 consecutive 1,000-yard seasons will finally slow down – but I’m not counting on that happening this year.
With Chris Godwin’s status for the start of the season in doubt and Jalen McMillan on injured reserve, Baker Mayfield and the Bucs will need to lean on Mike Evans to set the tone early. At 32, Evans is still up to the task. Even after missing three games last year, Evans nabbed 11 TDs on 110 targets and averaged 17.2 fantasy PPG (WR10), his best since 2019.
If you take Evans in Round 3 or 4, keep Mayfield in mind later. Since arriving in Tampa, he’s been a revelation, both for the franchise and fantasy managers.

Baker Mayfield’s Advanced Metrics
In 2024, Mayfield delivered his magnum opus: he was the QB4 overall, throwing for 4500 yards and 41 TDs. Mayfield also chipped in some nice production with his legs, rushing for 378 yards and 3 TDs. While I do think some TD regression is likely, Mayfield is once again set up to deliver big numbers in 2025 with the Bucs adding Ohio State WR Emeka Egbuka to the team.
Pairing these two won’t cost an arm and a leg, and it’ll deliver some weekly wins when they connect on a deep strike or two for six points.
4. QB Bo Nix & WR Courtland Sutton
This combo is the AFC West version of Mayfield and Evans in my opinion. At 6-3, Courtland Sutton is a true deep ball weapon, and in his first season catching passes from Bo Nix, he ranked:
- No. 2 in air yards
- No. 7 in deep targets
- No. 8 in red zone targets
- No. 9 in expected fantasy PPG

Courtland Sutton’s Advanced Metrics
Sutton turned those opportunities into a career year, finishing with 81 receptions, 1,081 receiving yards, and eight TDs. From Week 8 on, he was the WR7 in total points. That performance was rewarded when the Broncos gave him a 4-year, $92-million contract in July.
You can get Sutton in round 5 and lock in a solid WR2 or WR3 for your roster. And if you do that, adding Nix later in the draft makes a lot of sense. The no. 12 overall pick in last year’s draft put up some excellent numbers under the tutelage of head coach Sean Payton and averaged 19.4 fantasy PPG. He wrapped up his rookie campaign with 3,775 passing yards, 430 rushing yards, and 33 total TDs.
While many label Nix as just a dink-and-dunk passer, he actually ranked no. 3 in deep ball attempts (73) and no. 7 in air yards (4090) in the league last season. That aggressiveness complements Sutton’s strengths very well, and this combo could be even more dangerous in year two together.
Value Stack: QB Patrick Mahomes & TE Travis Kelce
Wild that two of the greatest ever at their positions are the cheapest they’ve ever been going into the 2025 season. In Mahomes’ case, he’s coming off the worst fantasy season of his career, which, for him, still meant nearly 4,000 yards and 28 total TDs. Kelce is approaching age 36, and, yes, he’s lost a step, but he hauled in 97 receptions for 823 yards. The only real dip came in the TD column, with just three during the regular season.
The Chiefs’ offense has evolved from Mahomes’ early years and doesn’t produce the same fireworks it once did, but this duo’s chemistry is still unmatched. Kelce remains Mahomes’ most trusted target when it matters most, and you can get them both in the middle rounds. That’s a rare bargain for a stack with a proven championship ceiling and league-winning history.
For more articles from PlayerProfiler, check out the fantasy home page – NFL Fantasy | PlayerProfiler – Fantasy Football News & Media
Wolf Trelles-Heard is a fantasy football contributor for PlayerProfiler. Find him on X at @DynastyFFWolf.

