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The Pittsburgh Steelers are coming off a win, but are a struggling team. Ben Roethlisberger can’t push the ball downfield and Najee Harris has been productive but inefficient. Big Ben’s play continues to drag the offense down, and only Diontae Johnson and Najee Harris are reliable assets.

The Minnesota Vikings are led by an under-appreciated quarterback, Kirk Cousins. Cousins has been pinpoint accurate and incredibly productive, propelling Justin Jefferson to another mind melting season. Without Adam Thielen, big boosts in opportunity will go to K.J. Osborn and Tyler Conklin. They’ll rely more on their stable running game to get the job done tonight.

Austin Ekeler did not play his best game last week, coughing the rock twice in what could have cost the Chargers the game. However, he still crushed for fantasy off the heels of another touchdown and five more receptions. Remember when Ekeler couldn’t score touchdowns? Me either. He’s already up to 15 (!!!) on the season. He has 45 red zone touches, which is No. 3 among running backs. This drastic change in usage around the goal line has transformed him into a league winner.

After registering three targets in his first two games of the season, Saquon Barkley has seen at least five in every other game. He just hauled in nine targets this last week after running 30 routes. The nine targets were the most he’s seen all season, and the 30 routes were tied for second on the team. His usage is elite, and he is set up to smash this week. The ride has been bumpy, but the payoff will come this week.

Jalen Hurts and Lamar Jackson are two upper echelon Konami QBs. Neither of these players are true “buy low” candidates, but their values have dipped recently. Both players are elite rushers and, while they aren’t the most efficient passers, they have the capability to explode through the air. Having an elite Konami QB is the key to winning championships, and this is your last chance to secure one.

Don’t look now, but Elijah Mitchell is a workhorse back. He’s received at least 25 touches in three straight games, and set a career high Snap Share in week 13. He has the athletic profile, he’s in the right offense, and he’s getting all of the carries. He’ll miss this week with a concussion, but after that it’s wheels up. Mitchell is a top five back for the rest of the season, and the season’s final buy of the week.

The PlayerProfiler and RotoUnderworld maestro of opportunities, head game analyst, and NFL draft analyst Cody Carpentier is back with the 2.0 version of his 2022 NFL Mock Draft to update movement from the College Football regular season to get you ready for Bowl Season.

Elijah Mitchell has been a great story in 2021. Congrats if you found him… (no, I made the mistake of drafting Trey Sermon!) During the upcoming offseason, though, quietly see what you might get in return. His price may never be higher. Don’t start any Bears other than David Montgomery. The new coaching staff and GM in 2022 will have to try to build around him and Justin Fields.

Javonte Williams will be an RB1 in 2022. But don’t feel too bad if you missed Williams but have Clyde Edwards-Helaire instead. He won’t see the same volume but, barring injury, will see enough action to be a reliable RB2. Don’t worry about Jalen Hurts. When his ankle heals, he’s Philadelphia’s starter.

Jerry Jeudy draws a Lions team that just allowed 340 passing yards and yielded plenty of separation to Vikings receivers. The only Lions corner in the top-40 of PlayerProfiler’s CB Rankings, Amani Oruwariye, just allowed a monster day to Justin Jefferson. Detroit has allowed over 300 yards through the air in each of its last two games. Expect Jeudy to get the opportunity for a massive fantasy day this week.

Before an A+ matchup against the Jaguars, Matthew Stafford threw 5 interceptions with a completion rate below 64-percent in the three games prior combined. Stafford has shown signs of struggle against good defenses, especially in the second half of the season. The Cardinals, meanwhile, have limited opposing QBs to less than 250 passing yards in six of their last seven games. Be wary of a tough matchup this week for Stafford.

Kenny Gainwell has been in this article multiple times, but this time he could stick and actually be usable in deep formats for the fantasy playoffs. Miles Sanders injured his ankle and Gainwell stepped in to catch five passes and rush 12 times for 54 yards and a TD. This backfield is very much in flux, but I want to try and add as much Gainwell as possible with the hopes that the rookie can be a useful fantasy play after the bye.

If you need a Flex or WR3 this week, K.J. Osborn is one of the best options. Adam Thielen suffered a high ankle sprain and Osborn saw his highest number of snaps of the season with 70. If Thielen misses more than a week, Osborn could be a helpful player in the playoffs as an every-down player on a team with a narrow target tree.

The New England Patriots are looking to plant their flag as the best team in the AFC. Mac Jones continues to improve and has established connections with Jakobi Meyers and Kendrick Bourne. Against the Bills, they’ll look to rely on Damien Harris and Rhamondre Stevenson to propel the offense through the run game.

The Bills have been inconsistent, and have dropped some bad games. Recently, Josh Allen and the offense have been rolling. Stefon Diggs has gotten back on track, and Cole Beasley has jumped back into the mix of production. The surprise of this team has been the resurgence of running back Matt Breida, who has quickly earned a significant role.

Some say the number 13 is unlucky… and perhaps it is. When it comes to football and injuries, no bad luck is needed. It’s week 13 of the NFL season and multiple high-profile names are on the list. Wether or not the accursed number has anything to do with it matters not. It’s a sport that delivers injuries quicker than Amazon delivers Christmas gifts. Speaking of gifts, The Infirmary is always here to give the gift of knowledge!

Vegas predicts that the divisional matchup between Tampa Bay and Atlanta will be the highest scoring game of the weekend, with a 50.5-point total. And the beloved Cordarrelle Patterson will be the beneficiary, hitting the OVER with ease. Patterson is one of the most efficient “running backs” in the NFL. His 12.2 (No. 1 among qualified running backs) Yards Per Reception and 6.8 (No. 1) Yards Per Touch will be on full display against Tom Brady and the Buccaneers.

Ja’Marr Chase is coming to smash the OVER in another game with a high total of 49.5 points. Three of the past four games were blowout victories for the Bengals, which have contributed to Chase’s subpar receiving yards. On the contrary, the competitive matchup against the Chargers will provide more opportunity for Chase to rack up yards with his 99.4-percent (No. 2) Route Participation and 41.6-percent (No. 4) Air Yards Share.