Isaac Guerendo is learning the 49ers offense for Kyle Shanahan. Guerendo did not have much experience playing in college until he transferred from Wisconsin to Louisville for his fifth-year senior season. He finished the season with 810 rushing yards with 11 touchdowns and 22 catches for 234 receiving yards.

When fantasy players saw Isaac Guerendo’s numbers from the combine, they had to scramble to figure out who the hell the guy is! For whatever reason Gurendo has never had a chance to truly carry a team on his back. Sadly, Guerendo will have a hard time getting on the field with the fantasy GOAT Christian McCaffrey playing. Guerendo is deep stash handcuff to McCaffrey. Should McCaffrey go down with injury, look for sparks to fly when Guerendo totes the rock!