San Francisco 49ers running back Isaac Guerendo is going to miss “a few weeks” with a shoulder injury, as per Kyle Shanahan. Jordan Mason’s trade to the Minnesota Vikings earlier this offseason seemed to indicate that Guerendo would be given the first opportunity to serve as backup to Christian McCaffrey. The injuries continue to pile up for the running back. In his rookie season, he missed time due to hamstring, groin, and foot injuries. In the season finale, he suffered an MCL sprain and an ankle sprain.

It is frustrating news to hear, as his skill and athleticism are on display when he is in the game. The 6-foot, 220-pound back has blazing speed (4.33 40), elite explosiveness, and is an above-average receiver. In a backfield that seems to be a revolving door of injuries, fantasy managers must be tapped into the news when it comes to the 49ers. Jordan James and Isaac Guerendo are dealing with injuries, and time will tell if Christian McCaffrey is back to full health.

When healthy, Guerendo will be a valuable handcuff to roster, and he did show production, finishing as an RB1 for three weeks in 2024.

Author: Dane Madoche(@FF_DaMaddog)